Active immunotherapy mobilizes the body's antitumor immunity and is meant to become the foundational support method in colorectal cancer — including at advanced stages.
Timely surgical treatment of colorectal cancer can lead to full recovery. However, at advanced stages, when radical surgery is impossible, the prognosis is poor — despite ongoing chemotherapy.
Therefore, immunotherapy aimed at mobilizing the body's antitumor immunity is meant to become a core method of treating this disease.
37 vaccinated patients with stage IV disease and 37 control group patients, matched by sex, age, localization, and tumor spread.
| Characteristic | Study Group | Control Group |
|---|---|---|
| Men / Women | 20 / 17 | 20 / 17 |
| Average age, years | 61.1 (38–79) | 48.2 (30–80) |
| Metastases: lymph nodes, soft tissues | 17 (46%) | 17 (46%) |
| Metastases: lungs | 8 (22%) | 6 (16%) |
| Metastases: liver | 27 (73%) | 19 (51%) |
| Metastases: other organs | 11 (30%) | 8 (22%) |
| Prior treatment: surgery | 19 (46%) | 17 (46%) |
| Prior treatment: surgery + chemotherapy | 8 (22%) | 6 (16%) |
All patients in the study group had disseminated cancer. The best results are expected when treatment starts immediately after conditionally radical surgery.
achieved a clinical effect
complete, partial response, or stabilization for at least 6 months (23 out of 37)
survivors by the end of observation
versus 3% (1 patient) in the control group
reliability of differences in 2-year survival
compared to the control group
Clinical cases demonstrate long-term stabilization in disseminated colorectal cancer.
Patient K., 46 years old
Stage III transverse colon cancer, poorly differentiated adenocarcinoma
Baseline
After colon resection, a 15 mm focal lesion in the liver was found — vaccine therapy was started. An additional mass 34 × 27 mm was found in the retroperitoneal space; therapy was intensified.
After 2 years
Ultrasound and CT showed no secondary changes in the liver. After 2.5 years, reconstructive surgery was performed — no signs of progression were noted.
Observation period
4 years after the start of treatment, the patient's condition remained satisfactory, with no signs of the disease observed.
No signs of disease — observed for 4 years
Patient T., 51 years old
Mucinous adenocarcinoma of the sigmoid colon
Baseline
Admitted with acute bowel obstruction; conditionally radical resection of the sigmoid and conglomerate was performed. Vaccination started under a standard regimen.
Dynamics
A 45 × 41 mm tissue mass in the left retroperitoneal space persisted, without negative dynamics during therapy.
Observation period
3.5 years after starting vaccine therapy, the patient felt well, with no signs of disease progression.
Stable condition — observed for 3.5 years
The best results are achieved when immunotherapy is started immediately after conditionally radical surgical intervention.
The best results are expected when treatment is initiated immediately after conditionally radical surgical intervention.
The method is applicable even in advanced stage IV cancer, when standard treatment options are limited.
Immunotherapy mobilizes your own antitumor immunity without placing a heavy toxic burden on the body.
Leave your contact details. Our medical coordinator will contact you shortly to answer any questions.