Immunotherapy for Prostate Cancer

Tumor-specific immunotherapy targets prostate cancer cells — independently or as an adjunct to other treatment methods.

12–18 moaverage time to hormone refractivity
≥ 6 moclinical effect in most stage IV patients

Active immunotherapy for prostate cancer

The primary treatment for metastatic prostate cancer is hormone therapy. However, over time, all patients stop responding to it: a hormone-refractory state develops on average 12–18 months after starting therapy.

The treatment of hormone-refractory cancer is mostly palliative and does not significantly affect life expectancy. Tumor-specific immunotherapy can be considered both as an independent treatment and as an addition to other methods.

Our experience shows: the clinical effect of xenovaccinotherapy lasting at least 6 months is achieved in the majority of stage IV patients. The results should be considered preliminary, as they were obtained in a small group of patients with advanced disease.

When immunotherapy is applicable

1

For hormone-refractory cancer

When the tumor stops responding to hormone therapy, immunotherapy provides an additional mechanism for attacking tumor cells.

2

Independently or combined

Tumor-specific immunotherapy can be used as a standalone treatment or in conjunction with other methods.

3

Without severe toxicity

The method does not carry the severe side effects characteristic of other types of antitumor treatment.

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