Scleroderma
We correct the immune response to stop excessive collagen production and protect internal organs.
About the disease
In scleroderma the immune system triggers excess collagen production, and connective tissue grows where it should not. The skin suffers, and in the systemic form so do the vessels, lungs, esophagus, and kidneys. Stopping this process matters more than fighting individual symptoms. That is what immunotherapy aims at.
We use T-cell autoimmunotherapy. It acts selectively on the immune cells that sustain the pathological response and does not suppress overall immunity. This sets it apart from steroids and cytostatics, which suppress the body's whole defense.
The goal of treatment is to slow fibrosis and protect internal organs while the changes are still reversible or have not gone far. The method is therefore especially relevant in early stages and in the systemic form with risk to the lungs and vessels.
Immunotherapy is built into the overall care plan alongside disease-modifying therapy. It complements the rheumatologist's treatment rather than canceling it.
The physician decides whether it is possible and how it is structured after assessing the form of scleroderma, disease activity, organ involvement, and records. There is no universal protocol; the program is tailored to each case.
Fibrosis control
The method slows the excess formation of connective tissue.
Protecting internal organs
Important in the systemic form with risk to the lungs and vessels.
Without general immunosuppression
The effect is selective; overall immunity is not suppressed.
Combines with disease-modifying therapy
Complements the rheumatologist's treatment rather than canceling it.
Early intervention
Greatest benefit before the changes go far.
T-cell vaccination
The method aims to stimulate immune reactions selectively directed at inactivating pathogenic autoimmune T-lymphocytes.
Collection and isolation
Autoaggressive T-lymphocytes — cells attacking the body's own tissues — are isolated from your blood.
Vaccine preparation
The isolated cells are processed and used to create a personalized T-cell vaccine.
Vaccination
Administering the vaccine triggers a regulatory immune response that selectively suppresses only the pathogenic cell clones.
Monitoring and support
Inflammatory activity decreases without suppressing general immunity; the course is adjusted based on dynamics.
Frequently asked questions
How does immunotherapy work in scleroderma?
The method acts selectively on the immune cells that sustain excess collagen production. This helps slow fibrosis and protect the skin and internal organs.
Is overall immunity suppressed?
No. Unlike steroids and cytostatics, T-cell autoimmunotherapy acts selectively and does not suppress the body's whole defense.
At what stage is the method most appropriate?
In early stages and in the systemic form with risk to the lungs, vessels, and esophagus, while the changes can still be brought under control. The physician gives a precise assessment after examination.
Can the method be combined with disease-modifying therapy?
Yes. Immunotherapy is built into the overall care plan alongside the rheumatologist's treatment; it complements it rather than replacing it.
How does the course of treatment go?
First a consultation and assessment of the form and activity of the disease. Then the physician builds an individual program. The method is tolerated more gently than long-term immunosuppressive therapy.
How much does treatment cost and can I come from another region?
The physician gives the exact cost after a consultation and review of records. The clinic is near Moscow (Khimki, Skhodnya) and accepts patients from other regions; the first consultation can be held remotely.
Other directions
Multiple sclerosis
Selective inactivation of aggressive lymphocytes to protect the myelin sheath of nerve fibers.
Ankylosing spondylitis
Targeted reduction of inflammatory activity in the spine, preventing joint fusion.
Autoimmune vasculitis
Relieving inflammation of the vascular wall to restore normal blood circulation.
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